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Syntax in C. elegans locomotion: A systems approach to behaviour

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Wednesday, April 23, 2014
2:00 pm - 3:00 pm
Andre Brown, MRC Clinical Science Centre, Imperial College, London
Duke Center for Systems Biology Seminars/Behavioral Biophysics Seminar

We have used inexpensive tracking microscopes to record the spontaneous behaviour of more than 10,000 worms from more than 330 strains, including mutants and wild isolates, at high resolution. In the context of this new data set, I will address two interrelated questions: how can we develop a framework for understanding behaviour quantitatively and how can we use this framework to advance behavioural genetics? Specifically, I will discuss unsupervised methods for detecting stereotyped behaviours and how these can be used for quantitative phenotypic comparisons and investigating behavioural adaptation and evolution.Special seminar series sponsored by the Office of the Dean of Natural Sciences and the Center for Systems Biology.Note location change: 103 Bryan Research Building