Investigating the Role of Environmental Polycyclic Aromatic Hydrocarbon Exposure on Breast Tumor Progression
What we know about the interaction between cancer and the environment is largely in the area of carcinogenesis/initiation, but it is perhaps just as crucial to consider a patient's environment after diagnosis and during the course of their disease and treatment. Emerging evidence suggests the role of environmental chemicals, in particular endocrine disrupting chemicals (EDCs), in progression of breast cancer and treatment resistance, which can impact survival outcomes. In a multi-scale approach, Risa uses tools from epidemiology, exposure analysis, and cell culture to study interactions between breast tumor progression and the environment toward an integrated analysis.
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