K63 ubiquitin and translation control in response to oxidative stress
In this seminar, Dr. Silva will discuss a recently discovered pathway of translation control in response to oxidative stress. Using a combination of proteomics, cryo-electron microscopy, cellular and molecular biology, his lab has characterized the key enzymatic players and many molecular mechanisms by which unconventional ubiquitination of ribosomes controls protein synthesis and supports resistance to oxidative stress.
Live Zoom presentation. Register to receive Zoom link at: https://duke.zoom.us/meeting/register/tJArdOmurjIuG9fQglBsNt2pzhguWVSueX9X