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CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Panel/Seminar/Colloquium
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=18832edc-1b31c518-011b-40a23061-00000095:Hester\, G
 lenda
CREATED:20250214T185420Z
DESCRIPTION:Abstract: During cardiovascular development\, peristaltic cont
 raction of the embryonic heart tube produces time-varying hemodynamic for
 ces and pressure gradients across the atrioventricular canal. However\, t
 he relative importance of myocardial contraction and hemodynamic force to
  modulate cardiovascular morphogenesis in the non-Newtonian flow regime r
 emains poorly understood. By developing the 4-D light-sheet fluorescent m
 icroscope and post-imaging machine-learning algorithms\, we recapitulate 
 flow-mediated molecular transducers underlying the vascular injury and re
 generation in the zebrafish vascular injury model. We further elucidate e
 xercise training-mediated transcriptomic interaction underlying activatio
 n of endothelial SCD1 to catalyze anti-inflammatory metabolites. In this 
 context\, we integrate multi-scale mechano-transcriptomic interaction fro
 m zebrafish to mouse models and demonstrate flow-responsive molecular tra
 nsducers as therapeutic targets for cardiovascular development\, repair\,
  and protection.
DURATION:PT1H
DTSTAMP:20250220T153019Z
DTSTART;TZID=America/New_York:20250227T100000
LAST-MODIFIED:20250220T153019Z
LOCATION;X-BEDEWORK-UID=8a08708a-32dad071-0132-f2e6e33e-00001131:Teer 106
STATUS:CONFIRMED
SUMMARY:Multi-Scale Biomechanics of Blood Flow for Vascular Development\, 
 Repair\, and Rejuvenation
UID:CAL-8a000483-92c3adf6-0195-05cfd27d-00001a57demobedework@mysite.edu
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 l_ECE,":Biomedical Engineering (BME)\,Civil and Environmental Engineering
  (CEE)\,Duke Materials Initiative\,Electrical and Computer Engineering (E
 CE)
X-BEDEWORK-SPEAKER:Tzung K. Hsiai\, MD\, PhD
X-BEDEWORK-SUBMITTEDBY:ghester for Mechanical Engineering and Materials Sc
 ience (MEMS) (agrp_PrattSchool_MEMS)
END:VEVENT
BEGIN:VEVENT

CATEGORIES:United States Focus
CATEGORIES:Diversity/Inclusion
CATEGORIES:Engineering
CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Research
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=8a03932d-8a96243a-018a-dcc45bf0-00000bc4:Adams\, Ha
 ppi
CREATED:20260127T185348Z
DESCRIPTION:Maternal mortality and poor fetal outcomes are rising in the U
 S. Join us to hear Dr. Michelle Oyen discuss opportunities for transforma
 tive research in pregnancy with the potential to save lives\, costs to th
 e healthcare system\, and human suffering.\n\nThursday\, February 26\n3:3
 0-4:30pm\nTeer 106\n\nRefreshments will be provided.
DURATION:PT1H
DTSTAMP:20260127T185348Z
DTSTART;TZID=America/New_York:20260226T153000
LAST-MODIFIED:20260127T185348Z
LOCATION;X-BEDEWORK-UID=8a08708a-32dad071-0132-f2e6e33e-00001131:Teer 106
STATUS:CONFIRMED
SUMMARY:Bioengineering Opportunities in Maternal Health
UID:CAL-8a00eca5-9af98aae-019c-00ce0ab0-0000664edemobedework@mysite.edu
URL:https://docs.google.com/forms/d/e/1FAIpQLScToI3cpzk_5pURC1drhIcZ9vtK5Q
 WR2www-qr89fGG9APq_w/viewform?usp=dialog
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 r/Topics/Engineering
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 blic-user/Topics/Diversity_Inclusion
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 )/United States Focus
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X-BEDEWORK-SPEAKER:Michelle L. Oyen\, Ph.D
X-BEDEWORK-DUKE-SERIES:Duke BME Culture & Belonging Seminar Series
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X-BEDEWORK-IMAGE-ALT-TEXT:Headshot of Dr. Michelle Owen. Blue background. 
 Text in black reads: Duke BME Culture & Belonging Seminar Series / Michel
 le L. Oyen\, Ph.D / "Bioengineering Opportunities in Maternal Health"
X-BEDEWORK-SUBMITTEDBY:mha32 for Biomedical Engineering (BME) (agrp_PrattS
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END:VEVENT
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