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2/19/2025 UPDATE: VIRTUAL ONLY: Studying Environmental Insults to Peri-implantation Human Pregnancy—Can Misguided Efforts in Reproductive Immunology Guide Us?

Seminar speaker, Dr. Danny Schust, wearing brown glasses and smiling
Thursday, February 20, 2025
12:00 pm - 1:15 pm
Danny Schust, M.D., Duke University
Integrated Toxicology & Environmental Health Seminar Series

Five decades of research in human reproductive immunology have resulted in an almost full erasure of proven tests and interventions for common disorders of early pregnancy (e.g., isolated and recurrent early pregnancy loss) and common disorders of abnormal placentation (pre-eclampsia and intrauterine growth restriction). However, we have learned from these misguided efforts that to study normal and anormal human peri-implantation biology, consistencies in species, timing and location are all essential. This lecture will use the many lessons learned from the study of human reproductive immunology as a case study on the informed development of in vitro models to study human peri-implantation biology, including their uses, advantages, limitations and misuses. The audience should come away with an excellent understanding of human reproductive immunology and a set of in vitro approaches that can be leveraged to study the effects of environmental toxins and exposures that can adversely impact human pre-implantation embryo development, embryo implantation, post-implantation placentation, the health of mother and baby during pregnancy and, ultimately, the long-term health trajectories of both the mother and her offspring.

THIS IS A VIRTUAL SEMINAR.
This seminar will be held via Zoom.
Visit the seminar website for the Zoom link.
Both attendance options (in person and virtual) are free and open to all.