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BEGIN:VEVENT

CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Research
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=2c918084-5da938ca-015d-c813d3bf-0000708b:Shipman\, 
 Dierdre
CREATED:20220328T194046Z
DESCRIPTION:The Duke CTN group welcomes Srini Turaga\, PhD\, group leader 
 at HHMI's Janelia Farms\, on Thursday 4/7\, at 10:30a. Dr. Turaga will pr
 esent "Visual selectivity emerges from connectome and task constraints in
  the fruit fly visual system" LIVE in 301 Bryan Research. ABSTRACT:Effort
 s to generate ``connectomes''\, or synaptic wiring diagrams\, of large ne
 ural circuits or entire nervous systems promise an abundance of data to i
 nform mechanistic models of neural computation. While connectomic studies
  have shown that neural circuits typically have sparse and highly structu
 red connectivity patterns\, it is yet unknown the degree to which such st
 ructure constrains mechanistic models of neural circuit function. We ask 
 if it is possible to predict the tuning properties of individual neurons 
 in real neural circuits\, given only measurements of neural connectivity\
 , simple assumptions about single neuron biophysics\, and a high-level un
 derstanding of the overall computational role of the circuit. We tested t
 his hypothesis by building a connectome-constrained model of the first tw
 o stages of the optic lobe of the \\textit{Drosophila} visual system. Amo
 ng ensembles of networks that were trained to predict optic flow\, we fre
 quently find networks that correctly predict motion tuning in the well-kn
 own motion selective T4 and T5 neurons. Our framework for using machine l
 earning to combine connnectomic constraints with task constraints paves t
 he path for the systematic combination of multiple ethologically relevant
  task constraints with measurements and perturbations of neural activity 
 and behavior.
DURATION:PT1H
DTSTAMP:20220328T194046Z
DTSTART;TZID=America/New_York:20220407T103000
LAST-MODIFIED:20220328T194046Z
LOCATION;X-BEDEWORK-UID=8a08708a-3336bd69-0133-6f20e794-000027b8:Bryan Res
 earch 301
STATUS:CONFIRMED
SUMMARY:CTN Seminar: Visual selectivity emerges from connectome and task c
 onstraints in the fruit fly visual system
UID:CAL-8a009144-7fb64372-017f-d20b8cf5-00007c9cdemobedework@mysite.edu
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Main:/user/public-user/Utili
 ties/Main
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Lecture_Talk:/user/public-us
 er/Lectures_Conferences/Lecture_Talk
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Research:/user/public-user/T
 opics/Research
X-BEDEWORK-CS;X-BEDEWORK-PARAM-DESCRIPTION="/principals/users/agrp_Institu
 teforBrainSciences,/principals/users/agrp_SchoolofMedicine,":Duke Institu
 te for Brain Sciences (DIBS)\,School of Medicine (SOM)
X-BEDEWORK-SPEAKER:Srini Turaga\, hosted by Eva Naumann
X-BEDEWORK-DUKE-SERIES:Computational and Theoretical Neuroscience Seminar 
 Series
X-BEDEWORK-SUBMITTEDBY:shipm003 for Neurobiology (agrp_SchoolofMedicine_Ne
 urobiology)
END:VEVENT
END:VCALENDAR