BEGIN:VCALENDAR
PRODID:BedeWork V3.5
VERSION:2.0
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:America/New_York
X-LIC-LOCATION:America/New_York
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20070311T020000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20071104T020000
RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU
END:STANDARD
BEGIN:STANDARD
TZOFFSETFROM:-045602
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:18831118T120358
RDATE:18831118T120358
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:19180331T020000
RDATE:19180331T020000
RDATE:19190330T020000
RDATE:19200328T020000
RDATE:19210424T020000
RDATE:19220430T020000
RDATE:19230429T020000
RDATE:19240427T020000
RDATE:19250426T020000
RDATE:19260425T020000
RDATE:19270424T020000
RDATE:19280429T020000
RDATE:19290428T020000
RDATE:19300427T020000
RDATE:19310426T020000
RDATE:19320424T020000
RDATE:19330430T020000
RDATE:19340429T020000
RDATE:19350428T020000
RDATE:19360426T020000
RDATE:19370425T020000
RDATE:19380424T020000
RDATE:19390430T020000
RDATE:19400428T020000
RDATE:19410427T020000
RDATE:19460428T020000
RDATE:19470427T020000
RDATE:19480425T020000
RDATE:19490424T020000
RDATE:19500430T020000
RDATE:19510429T020000
RDATE:19520427T020000
RDATE:19530426T020000
RDATE:19540425T020000
RDATE:19550424T020000
RDATE:19560429T020000
RDATE:19570428T020000
RDATE:19580427T020000
RDATE:19590426T020000
RDATE:19600424T020000
RDATE:19610430T020000
RDATE:19620429T020000
RDATE:19630428T020000
RDATE:19640426T020000
RDATE:19650425T020000
RDATE:19660424T020000
RDATE:19670430T020000
RDATE:19680428T020000
RDATE:19690427T020000
RDATE:19700426T020000
RDATE:19710425T020000
RDATE:19720430T020000
RDATE:19730429T020000
RDATE:19740106T020000
RDATE:19750223T020000
RDATE:19760425T020000
RDATE:19770424T020000
RDATE:19780430T020000
RDATE:19790429T020000
RDATE:19800427T020000
RDATE:19810426T020000
RDATE:19820425T020000
RDATE:19830424T020000
RDATE:19840429T020000
RDATE:19850428T020000
RDATE:19860427T020000
RDATE:19870405T020000
RDATE:19880403T020000
RDATE:19890402T020000
RDATE:19900401T020000
RDATE:19910407T020000
RDATE:19920405T020000
RDATE:19930404T020000
RDATE:19940403T020000
RDATE:19950402T020000
RDATE:19960407T020000
RDATE:19970406T020000
RDATE:19980405T020000
RDATE:19990404T020000
RDATE:20000402T020000
RDATE:20010401T020000
RDATE:20020407T020000
RDATE:20030406T020000
RDATE:20040404T020000
RDATE:20050403T020000
RDATE:20060402T020000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:19181027T020000
RDATE:19181027T020000
RDATE:19191026T020000
RDATE:19201031T020000
RDATE:19210925T020000
RDATE:19220924T020000
RDATE:19230930T020000
RDATE:19240928T020000
RDATE:19250927T020000
RDATE:19260926T020000
RDATE:19270925T020000
RDATE:19280930T020000
RDATE:19290929T020000
RDATE:19300928T020000
RDATE:19310927T020000
RDATE:19320925T020000
RDATE:19330924T020000
RDATE:19340930T020000
RDATE:19350929T020000
RDATE:19360927T020000
RDATE:19370926T020000
RDATE:19380925T020000
RDATE:19390924T020000
RDATE:19400929T020000
RDATE:19410928T020000
RDATE:19450930T020000
RDATE:19460929T020000
RDATE:19470928T020000
RDATE:19480926T020000
RDATE:19490925T020000
RDATE:19500924T020000
RDATE:19510930T020000
RDATE:19520928T020000
RDATE:19530927T020000
RDATE:19540926T020000
RDATE:19551030T020000
RDATE:19561028T020000
RDATE:19571027T020000
RDATE:19581026T020000
RDATE:19591025T020000
RDATE:19601030T020000
RDATE:19611029T020000
RDATE:19621028T020000
RDATE:19631027T020000
RDATE:19641025T020000
RDATE:19651031T020000
RDATE:19661030T020000
RDATE:19671029T020000
RDATE:19681027T020000
RDATE:19691026T020000
RDATE:19701025T020000
RDATE:19711031T020000
RDATE:19721029T020000
RDATE:19731028T020000
RDATE:19741027T020000
RDATE:19751026T020000
RDATE:19761031T020000
RDATE:19771030T020000
RDATE:19781029T020000
RDATE:19791028T020000
RDATE:19801026T020000
RDATE:19811025T020000
RDATE:19821031T020000
RDATE:19831030T020000
RDATE:19841028T020000
RDATE:19851027T020000
RDATE:19861026T020000
RDATE:19871025T020000
RDATE:19881030T020000
RDATE:19891029T020000
RDATE:19901028T020000
RDATE:19911027T020000
RDATE:19921025T020000
RDATE:19931031T020000
RDATE:19941030T020000
RDATE:19951029T020000
RDATE:19961027T020000
RDATE:19971026T020000
RDATE:19981025T020000
RDATE:19991031T020000
RDATE:20001029T020000
RDATE:20011028T020000
RDATE:20021027T020000
RDATE:20031026T020000
RDATE:20041031T020000
RDATE:20051030T020000
RDATE:20061029T020000
END:STANDARD
BEGIN:STANDARD
TZOFFSETFROM:-0500
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:19200101T000000
RDATE:19200101T000000
RDATE:19420101T000000
RDATE:19460101T000000
RDATE:19670101T000000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EWT
DTSTART:19420209T020000
RDATE:19420209T020000
END:DAYLIGHT
BEGIN:DAYLIGHT
TZOFFSETFROM:-0400
TZOFFSETTO:-0400
TZNAME:EPT
DTSTART:19450814T190000
RDATE:19450814T190000
END:DAYLIGHT
END:VTIMEZONE
BEGIN:VEVENT

CATEGORIES:Natural Sciences
CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=00f1fcdb-0f068baf-010f-068baf83-00000004:None
CREATED:20220906T141844Z
DESCRIPTION:"The Simmons-Smith Reaction in the Age of Catalysis"\n\nSpeake
 r: Prof. Christopher Uyeda\, Richard B. Wetherill Professor of Chemistry\
 , Purdue University\n\nCarbenes are versatile reactive intermediates that
  display orthogonal reactivity to common nucleophilic and electrophilic f
 unctional groups. Homogeneously catalyzed carbene transfer reactions were
  first discovered over a half century ago\, and numerous examples of [n +
  1]-cycloaddition reactions have now been developed\, often with control 
 over diastereo- and enanatioselectivity. Nearly all of these reactions re
 ly on the controlled decomposition of diazoalkane precursors as a central
  strategy for accessing reactive carbene equivalents.\n\nDespite the util
 ity of diazoalkanes in organic synthesis\, they are inherently limited by
  the need for stabilizing substituents such as aryl or carbonyl groups. I
 n order to develop transfer reactions of non-stabilized carbenes\, such a
 s methylene\, isopropylidene\, and vinylidene\, it would be necessary to 
 identify an alternative set of precursors. Our group has shown that nicke
 l and cobalt catalysts can promote reductive [n + 1]-cycloaddition reacti
 ons using readily available and indefinitely stable 1\,1-dichloroalkanes 
 and 1\,1-dichloroalkenes as carbene precursors. In this seminar\, I will 
 describe our development of new cycloaddition methods and our current hyp
 otheses about the mechanisms of these reactions.\n\n\nTo learn more about
  the Uyeda lab and their research\, please visit: https://www.chem.purdue
 .edu/uyeda/.\n\nFaculty Host: Prof. Steven Malcolmson
DURATION:PT1H30M
DTSTAMP:20230104T215034Z
DTSTART;TZID=America/New_York:20230124T114000
LAST-MODIFIED:20230104T215034Z
LOCATION;X-BEDEWORK-UID=18832edc-1b27e154-011b-28282e22-00000037:French Fa
 mily Science Center 2237
STATUS:CONFIRMED
SUMMARY:Chemistry Seminar Presented by Prof. Christopher Uyeda: "The Simmo
 ns-Smith Reaction in the Age of Catalysis"
UID:CAL-8a038cd8-82f8ec9d-0183-132af667-00006d68demobedework@mysite.edu
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Main:/user/public-user/Utili
 ties/Main
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Lecture_Talk:/user/public-us
 er/Lectures_Conferences/Lecture_Talk
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Natural Sciences:/user/publi
 c-user/Topics/Natural Sciences
X-BEDEWORK-STUDENT-CONTACT;X-BEDEWORK-PARAM-EMAIL=chem-office@duke.edu:Dep
 artment of Chemistry
X-BEDEWORK-SPEAKER:Prof. Christopher Uyeda
X-BEDEWORK-DUKE-SERIES:Chemistry Department Seminar Series
X-BEDEWORK-IMAGE-X1:320
X-BEDEWORK-IMAGE-Y1:164
X-BEDEWORK-IMAGE-X2:2146
X-BEDEWORK-IMAGE-Y2:1381.3333333333333
X-BEDEWORK-IMAGE-CROP-WIDTH:1826
X-BEDEWORK-IMAGE-CROP-HEIGHT:1217.3333333333333
X-BEDEWORK-IMAGE-ALT-TEXT:Prof. Christopher Uyeda
X-BEDEWORK-SUBMITTEDBY:cconti for Chemistry (agrp_ArtsandSciences_Chemistr
 y)
X-BEDEWORK-IMAGE:/public/Images/Uyeda_20220906021844PM.jpg
X-BEDEWORK-THUMB-IMAGE:/public/Images/Uyeda_20220906021844PM-thumb.png
END:VEVENT
END:VCALENDAR