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BEGIN:VEVENT

CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Panel/Seminar/Colloquium
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=18832e99-20476e5b-0120-587daa86-000000bc:Burns\, Au
 gust
CREATED:20240821T194822Z
DESCRIPTION:By examining molecules one at a time\, single-molecule techniq
 ues capture rare and asynchronous events\, revealing rich mechanistic det
 ail that complements and deepens our understanding from bulk experiments.
  The Squires Group at the University of Chicago specializes in creating a
 nd using new spectroscopic "windows and handles"\; experimental platforms
  that expand our ability to directly observe and perturb single molecules
 . Our unique toolset enables us to record\, understand\, and control comp
 lex\, dynamic energy transfer patterns in both natural and engineered mac
 romolecular systems. I will present our latest updates to our single-part
 icle spectroscopy platform\, the Anti-Brownian ELectrokinetic (ABEL) trap
 \, and highlight two recent applications to (1) understand the Orange Car
 oteinoid Protein (OCP)-based photoadaptation response in cyanobacteria un
 dergoing photosynthesis\, and (2) to rationally design dozens of compound
  fluorescent labels from a minimal set of building blocks to enable wash-
 free labeling and detection of dozens of molecular species in low-concent
 ration mixtures.te the suitability of these devices for improving Raman s
 pectroscopy for real-world applications.\n\nProf. Allison Squires is the 
 Neubauer Family Assistant Professor of Molecular Engineering in the Pritz
 ker School of Molecular Engineering. The Squires Group's interdisciplinar
 y research centers on sensing\, imaging\, and manipulating nanoscale proc
 esses including energy transfer in biophysical systems. Squires holds a B
 SE in mechanical and aerospace engineering from Princeton University and 
 received her PhD in biomedical engineering as an NSF and Clare Boothe Luc
 e Fellow at Boston University\, where she worked on solid-state nanopores
  as single-biomolecule sensors. Prior to opening her lab at the Universit
 y of Chicago\, Prof. Squires completed post-doctoral training in the Chem
 istry Department at Stanford University\, where she pioneered the ISABEL 
 trap\, a new platform for trapping and spectroscopy of single particles a
 nd protein complexes in free solution. Squires is a Chan-Zuckerberg Inves
 tigator and a DOE Early Career Investigator. Web: https://squireslab.uchi
 cago.edu/
DURATION:PT1H
DTSTAMP:20241030T175457Z
DTSTART;TZID=America/New_York:20241106T120000
LAST-MODIFIED:20241030T175457Z
LOCATION;X-BEDEWORK-UID=18832e99-20476e5b-0120-58864347-000000be:Fitzpatri
 ck Center Schiciano Auditorium Side A\, room 1464
STATUS:CONFIRMED
SUMMARY:FIP Seminar: Single-particle-level understanding and control of ph
 otophysics in biomolecules
UID:CAL-8a00048d-91324965-0191-767baee6-00003251demobedework@mysite.edu
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Main:/user/public-user/Utili
 ties/Main
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Lecture_Talk:/user/public-us
 er/Lectures_Conferences/Lecture_Talk
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Panel_Seminar_Colloquium:/us
 er/public-user/Lectures_Conferences/Panel_Seminar_Colloquium
X-BEDEWORK-SPEAKER:Dr. Allison Squires\, Neubauer Family Assistant Profess
 or of Molecular Engineering\, Pritzker School of Molecular Engineering\, 
 University of Chicago
X-BEDEWORK-SUBMITTEDBY:ahb11 for Fitzpatrick Institute for Photonics (FIP)
  (agrp_FitzpatrickInstitute)
END:VEVENT
END:VCALENDAR