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BEGIN:VEVENT

CATEGORIES:Medicine
CATEGORIES:Engineering
CATEGORIES:Natural Sciences
CATEGORIES:Lectures/Conferences
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Panel/Seminar/Colloquium
CATEGORIES:Research
CATEGORIES:Technology
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=8a0183a7-83184018-0184-f88b4dd1-00001a24:Franklin\,
  Monica
CREATED:20230805T023014Z
DESCRIPTION:The Johri lab is interested in better characterizing the shape
  of the distribution of fitness effects of new mutations in organisms and
  on understanding how selection on functionally important regions affects
  genome-wide patterns of variation. Population genomic inference currentl
 y does not account for the effects of selection across the genome\, which
  is especially problematic in species with compact genomes (i.e.\, those 
 with a high density of protein-coding and regulatory regions) where natur
 al selection is pervasive. We develop statistical and computational metho
 ds that simultaneously account for the effects of selection jointly with 
 other evolutionary processes to make accurate evolutionary inferences (su
 ch as historical changes in population size) using sequence variation fro
 m natural populations. As most pathogenic species tend to have highly com
 pact genomes and experience strong bouts of selection and drastic repeate
 d bottlenecks\, our methodological advances and recent theoretical effort
 s will be important to uncovering their population and selective history.
 
DURATION:PT1H
DTSTAMP:20260209T020656Z
DTSTART;TZID=America/New_York:20260216T120000
LAST-MODIFIED:20260209T020656Z
LOCATION;X-BEDEWORK-UID=18832edc-1c2ecfef-011c-481f44ec-0000030a:French Fa
 mily Science Center 4233
STATUS:CONFIRMED
SUMMARY:Jointly Modeling the Effects of Evolutionary Processes on Genomic 
 Variation
UID:CAL-8a00eca5-9af98aae-019c-40222334-00005922demobedework@mysite.edu
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Main:/user/public-user/Utili
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X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Engineering:/user/public-use
 r/Topics/Engineering
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Medicine:/user/public-user/T
 opics/Medicine
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Natural Sciences:/user/publi
 c-user/Topics/Natural Sciences
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Research:/user/public-user/T
 opics/Research
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Lecture_Talk:/user/public-us
 er/Lectures_Conferences/Lecture_Talk
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Panel_Seminar_Colloquium:/us
 er/public-user/Lectures_Conferences/Panel_Seminar_Colloquium
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Technology:/user/public-user
 /Topics/Technology
X-BEDEWORK-CS;X-BEDEWORK-PARAM-DESCRIPTION="/principals/users/agrp_Artsand
 Sciences_Biology,/principals/users/agrp_SchoolofMedicine_Biostatisticsand
 Bioinformatics,/principals/users/agrp_Pratt_CAGT,/principals/users/agrp_C
 enterforGenomicandComputationalBiology,/principals/users/agrp_SchoolofMed
 icine_MolecularGenetics,/principals/users/agrp_SchoolofMedicine_Neurobiol
 ogy,/principals/users/agrp_SchoolofMedicine_CMB,/principals/users/agrp_Sc
 hoolofMedicine,/principals/users/agrp_SchoolofMedicine_UPGG,":Biology\,Bi
 ostatistics and Bioinformatics\,Center for Advanced Genomic Technologies\
 ,Duke Center for Genomic and Computational Biology (GCB)\,Molecular Genet
 ics and Microbiology (MGM)\,Neurobiology\,Program in Cell and Molecular B
 iology\,School of Medicine (SOM)\,University Program in Genetics &amp\;am
 p\;amp\;amp\;amp\;amp\;amp\;amp\; Genomics (UPGG)
X-BEDEWORK-SPEAKER:Parul Johri\, PhD
X-BEDEWORK-DUKE-SERIES:CBB Monday Seminar Series
X-BEDEWORK-IMAGE-X1:0
X-BEDEWORK-IMAGE-Y1:0
X-BEDEWORK-IMAGE-X2:529.5
X-BEDEWORK-IMAGE-Y2:353
X-BEDEWORK-IMAGE-CROP-WIDTH:529.5
X-BEDEWORK-IMAGE-CROP-HEIGHT:353
X-BEDEWORK-IMAGE-ALT-TEXT:Parul Johri
X-BEDEWORK-SUBMITTEDBY:monicaf for Computational Biology and Bioinformatic
 s (CBB) (agrp_SchoolofMedicine_CBB)
X-BEDEWORK-IMAGE:/public/Images/Parul Johri canva photo_20260209020144AM.j
 pg
X-BEDEWORK-THUMB-IMAGE:/public/Images/Parul Johri canva photo_202602090201
 44AM-thumb.png
END:VEVENT
END:VCALENDAR