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BEGIN:VEVENT

CATEGORIES:Engineering
CATEGORIES:Lectures/Conferences
CATEGORIES:Other
CATEGORIES:Utilities
CATEGORIES:Lecture/Talk
CATEGORIES:Panel/Seminar/Colloquium
CATEGORIES:Academic Calendar Dates
CATEGORIES:Research
CATEGORIES:Technology
CATEGORIES:Main
CONTACT;X-BEDEWORK-UID=00f1fcdb-0f068baf-010f-068baf83-00000004:None
CREATED:20260901T122028Z
DESCRIPTION:A central challenge in brain science is the relation between t
 he structure and the function of the nervous system. Modern approaches to
  this problem get inspiration from the efforts of Cajal\, more than 100 y
 ears\, ago to map neural connections\, but his work was insufficient in m
 any ways. Now\, with the advent of complete high-resolution descriptions 
 of brain structure in which all the brain's synaptic wiring can in princi
 ple be mapped (connectomics)\, new technical and interpretive problems ar
 ise. Currently\, whole brain connectomics is just getting underway and ma
 ny bioengineering and computational challenges will need to be met before
  entire mammalian brains are mapped at the level of synapses. Perhaps the
  most significant of these challenges is how we extract understanding fro
 m the unprecedented complexity and size of the datasets coming our way.  
      \n\nJeff W. Lichtman M.D.\, Ph.D. is Jeremy R Knowles Professor of M
 olecular and Cellular Biology\,  Ramon y Cajal Professor of Arts and Scie
 nces\, and John Harvard Professor in the Faculty of Arts and Sciences at 
 Harvard University. He was an undergraduate at Bowdoin College and receiv
 ed and MD and Ph.D. (with Dale Purves) at Washington University in St. Lo
 uis in 1980.  After a postdoc in the Neurobiology Department at Harvard M
 edical School\, he returned to St. Louis where he stayed before joining t
 he Molecular and Cellular Biology Department at Harvard in 2004. From his
  graduate work onwards\, he has developed approaches to map neural connec
 tions at the synapse level. Lichtman's research interest revolves around 
 the question of how mammalian brain circuits are physically altered by ex
 periences\, especially in early life.  He has focused on the dramatic re-
 wiring of neural connections that takes place in early postnatal developm
 ent when animals are doing most of their learning. This work has required
  development of techniques such as "Brainbow" transgenic mice to visualiz
 e neural connections and monitor how they are altered over time.  Recentl
 y his efforts have focused on developing new electron microscopy methods 
 to map the entire wiring diagram of the developing and adult brain.  This
  "connectomics" approach has as one of its aims uncovering the ways infor
 mation is stored in neural networks. Current efforts include generation o
 f the first synapse-level full vertebrate connectome (in a fish) and deve
 loping approaches for the whole mouse brain connectome.
DURATION:PT2H
DTSTAMP:20260901T122028Z
DTSTART;TZID=America/New_York:20260917T150000
LAST-MODIFIED:20260901T122028Z
LOCATION;X-BEDEWORK-UID=8a00eca5-9af98aae-019c-203177d8-00002ebc:Wilkinson
  021
STATUS:CONFIRMED
SUMMARY:Distinguished Seminar Series with Jeff Lichtman
UID:CAL-8a002cbd-9fb2e569-01a0-5ce9ea1c-00004088demobedework@mysite.edu
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Main:/user/public-user/Utili
 ties/Main
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Lecture_Talk:/user/public-us
 er/Lectures_Conferences/Lecture_Talk
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Panel_Seminar_Colloquium:/us
 er/public-user/Lectures_Conferences/Panel_Seminar_Colloquium
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Engineering:/user/public-use
 r/Topics/Engineering
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 opics/Research
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 /Topics/Technology
X-BEDEWORK-ALIAS;X-BEDEWORK-PARAM-DISPLAYNAME=Academic Calendar Dates:/use
 r/public-user/Other/Academic Calendar Dates
X-BEDEWORK-SPEAKER:Jeff Lichtman
X-BEDEWORK-SUBMITTEDBY:cm671 for Biomedical Engineering (BME) (agrp_PrattS
 chool_BME)
X-BEDEWORK-STUDENT-CONTACT;X-BEDEWORK-PARAM-EMAIL=junjie.yao@duke.edu:Dr. 
 Junjie Yao
END:VEVENT
END:VCALENDAR