How development scaffolds internal hippocampal dynamics

The Cossart lab studies the circuit basis of hippocampal assemblies from development into adulthood and across different states of the normal and pathological brain. To describe the circuit basis of cortical dynamics, they have developed a unique multidisciplinary approach that combines in vitro and in vivo calcium imaging, electrophysiology, holographic photo-stimulation, neuroanatomy, data mining, mouse genetics and behavior. In this talk Dr. Cossart will present both published and unpublished data from her lab indicating that internal hippocampal dynamics are remarkably structured and organized and that this functional organization is set very early during development.