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Fokker-Planck equations of neuron networks: justification and numerical simulation

Mathematical Biology Seminar
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Friday, April 09, 2021
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12:00 pm - 1:00 pm
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Zhennan Zhou
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Mathematical Biology Seminar

In this talk, we are concerned with the Fokker-Planck equations associated with the Nonlinear Noisy Leaky Integrate-and-Fire model for neuron networks. Due to the jump mechanism at the microscopic level, such Fokker-Planck equations are endowed with an unconventional structure: transporting the boundary flux to a specific interior point. In the first part of the talk, we present an alternative way to derive such Fokker-Planck equations from the microscopic model based on a novel iterative expansion. With this formulation, we prove that the probability density function of the "leaky integrate-and-fire" type stochastic process is a classical solution to the Fokker-Planck equation. Secondly, we propose a conservative and positivity preserving scheme for these Fokker-Planck equations, and we show that in the linear case, the semi-discrete scheme satisfies the discrete relative entropy estimate, which essentially matches the only known long time asymptotic solution property. We also provide extensive numerical tests to verify the scheme properties, and carry out several sets of numerical experiments, including finite-time blowup, convergence to equilibrium and capturing time-period solutions of the variant models.



Email ciocanel@math.duke.edu to request the Zoom link and password for the talk (or subscribe to announcements at https://lists.duke.edu/sympa/info/mathbio-seminar).