Skip to main content
Browse by:
GROUP

Effective March 10, 2020, all Duke-sponsored events over 50 people have been cancelled, rescheduled, postponed or virtualized.
Please check with the event contact regarding event status. For more information, please see https://coronavirus.duke.edu/events

Leveraging olfaction to study innate behavior in the mouse

Event Image
Icon calendar
Tuesday, December 11, 2018
Icon time
12:00 pm - 1:00 pm
Icon speaker
Lisa Stowers; hosted by Kevin Franks
Icon series
Neurobiology Invited Seminar Series

Survival behaviors such as aggression, fear, and mating are highly conserved across evolution. Knowing when and how to display survival behavior is essential for fitness and requires neural activity from known brain regions such as the amygdala and hypothalamus. However, the identity of the precise neurons and circuits that generate these survival behaviors remains largely unknown and therefore unstudied. In the mouse, these essential behaviors can be robustly initiated by olfactory cues. We have identified bioactive odors that now enable us to precisely stimulate and identify the circuits across the brain that generate behavior. By manipulating these subsets of neurons that translate a sensory signal into innate behavior we are creating a platform to begin to study the logic of their coding under 'normal' conditions, and how the sensory information elicits variable responses depending on state, gender, or the complexity of the environment.