Discovering and targeting repeat expansions in human disease
![Graham Erwin Graham Erwin](/images/2023/20230126/5cac6e4983f97b45eb93ad2cac5bf013-CR-Graham Erwin_20221221045910PM.jpg)
Expansion of a single repetitive DNA sequence, termed a tandem repeat (TR), is known to cause more than 50 diseases. However, repeat expansions are often not explored beyond neurological and neurodegenerative disorders. Here, I will discuss efforts to identify and target repeat expansions in human disease, with a focus on neurodegenerative disease and cancer.
Contact Greg Crawford (greg.crawford at duke dot edu) and Debby Silver (debra.silver at duke dot edu) with any questions.
Contact: Pat Massard