FIP Virtual Seminar: Title TBD

Registration coming soon.....

The Single-Molecule Imaging Group develops and applies single-molecule imaging approaches to study how structural dynamics regulate fundamental biological processes involving proteins and nucleic acids across scales (from molecules to cells). We are particularly interested in elucidating various mechanistic aspects of DNA and RNA processing, such as chromatin structure and remodelling, DNA replication and repair, and RNA transcription, splicing and localization. Single-Molecule Microscopy reveals the structural dynamics of individual molecules, otherwise hidden in ensemble-averaged experiments, thus enabling us to directly observe key reaction intermediates, even when short-lived or at low levels.