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Cerebellar control of reaching movements

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Tuesday, December 15, 2020
12:00 pm - 1:00 pm
Abigail Person, hosted by David Herzfeld
Neurobiology Invited Seminar Series

Duke Neurobiology welcomes Abigail Person, Associate Professor of Physiology and Biophysics at the University of Colorado School of Medicine. Contact d.shipman@duke.edu for connection details.
Abstract: The cerebellum is well appreciated to impart speed, smoothness, and precision to skilled movements such as reaching. How these functions are executed by the final output stage of the cerebellum, the cerebellar nuclei, remains unknown. In this talk, I will discuss our data identifying a causal relationship between cerebellar output and mouse reach kinematics and show how that relationship is leveraged endogenously to enhance reach precision. I will discuss how our results provide a framework for understanding the physiology and pathophysiology of the intermediate cerebellum during precise skilled movements.