Pathology Grand Rounds - Multiple Myeloma as an Enhanceropathy: Clinical Implications

Upon completion of this activity, learners should be able to:

* Describe six main genetic subtypes of MM, their prognosis, and the mechanisms of progression

* Explain how small molecules used for the treatment of MM each target plasma cell super-enhancers

* Review novel approaches to targeting enhancer dysregulation in MM

* Discuss how preclinical mouse models of MM can be used to study pathogenesis, targeted and immune therapies