Sigma-Aldrich Lecture Presented by Prof. Richmond Sarpong: Break-it-to-Make-it Strategies for Chemical Synthesis Inspired by Complex Natural Products"

"Break-it-to-Make-it Strategies for Chemical Synthesis Inspired by Complex Natural Products"

Natural products continue to inspire and serve as the basis of new medicines. They also provide intricate problems that expose limitations in the strategies and methods employed in chemical synthesis. Several strategies and methods that have been developed in our laboratory and applied to the syntheses of architecturally complex natural products will be discussed. In particular, new ways to employ the cleavage of core bonds such as C-C and C-N bonds (i.e., break-it-to-make-it strategies) to achieve skeletal editing will be presented.

The Department of Chemistry will host the 2023 Sigma-Adrich Lecture on April 25. The Lecture will be presented by Prof. Richmond Sarpong of the University of California at Berkeley. Learn more about Prof. Sarpong's development of novel strategies and methodologies in pursuit of constructing complex synthetic targets with intriguing biological activity on his research site (https://sarponggroup.com/research/).