Ruth K. Broad Seminar: Jim Hudspeth: Making an effort to listen: mechanical amplification by hair cells of the inner ear
Dr. Hudspeth is interested in the development and regenerative properties of the inner ear's sensory receptors, the hair cells. Hudspeth and his team investigate the structure and operation of hair cells in the hope of laying the groundwork for an understanding of normal hearing as well as its deterioration and restoration. They employ a variety of approaches, including biophysics, electrophysiology, developmental biology, biochemistry, genetics, molecular biology, immunology, and ultrastructural analysis. In addition, they assimilate their findings into mathematical models of hair-cell function.