Medicine Grand Rounds: The Path to Pegloticase for Refractory Gout – Intrapreneurial Drug Development at Duke

Drs. Michael Hershfield, Professor of Medicine and Biochemistry, Division of Rheumatology and Immunology & John Sundy, Adjunct Professor in the Department of Medicine will present "The Path to Pegloticase for Refractory Gout Intrapreneurial Drug Development at Duke"

Learning Objectives:
-To appreciate the clinical consequences of inadequately treated chronic gout
-To understand the potential advantages and disadvantages of replacement therapy with PEGylated enzymes
-To review the development of PEG-enzyme therapy for two disorders of purine metabolism
-To appreciate opportunities for translational laboratory-based research at Duke