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Microfluidic Circulation: Closing the Loop from In Vitro to In Vivo and from Single Cell to Tissue-Scale

Duke Mechanical Engineering & Materials Science
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Wednesday, March 20, 2019
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12:00 pm - 1:00 pm
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Dr. Abraham Lee | University of California, Irvine
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MEMS Seminar Series

The circulation system is a critical physiological process of the human body that maintains homeostasis by balancing biological parameters by the delivery and removal of nutrients/waste and fighting off invading pathogens. Through the advancement of microfluidics technologies, we have enabled the automation of biological fluids delivery through physiological vasculature networks that mimic the physiological circulation of the human body. The critical bottleneck is to engineer the microenvironment for the formation of 3D tissues and organs and to also pump and perfuse the tissue vascular network for on-chip microcirculation.

Abraham (Abe) P. Lee is the William J. Link Professor and Chair of the Biomedical Engineering (BME) Department with a courtesy appointment in Mechanical and Aerospace Engineering (MAE) at the University of California, Irvine. He is the Director of the NSF I/UCRC "Center for Advanced Design & Manufacturing of Integrated Microfluidics" (CADMIM). Prior to UCI, he was at the National Cancer Institute and a program manager in the Microsystems Technology Office at DARPA (1999-2001). Dr. Lee's lab focuses on developing active integrated microfluidics and droplet microfluidic platforms.

Lunch will be served at 11:30 am
Hosted by Dr. Tony Huang