Investigating the impact of chemicals on mitochondrial DNA mutagenesis
Understanding the causes and consequences of mitochondrial DNA mutations is a shared research interest across many fields of biology, ranging from evolutionary biology to human health. This is a challenging endeavor, as mitochondrial genetics is extraordinarily complex. However, advanced sequencing technologies has significantly improved the ability to detect mitochondrial DNA mutations. Here, Tess Leuthner, PhD Candidate, will discuss how we have taken multiple approaches across the three organisms C. elegans, Daphnia, and killifish to investigate the effect of various chemical exposures on mitochondrial DNA mutation rates.